Bio Claire cream is used in short courses to treat severe inflammatory skin disorders, such as those below, when milder corticosteroids have not been effective. Bio Claire cream contain the active ingredient clobetasol propionate, which is a type of medicine called a topical corticosteroid. Corticosteroids (also known as steroids) are medicines used for reducing inflammation. Skin inflammation may occur as a result of an allergic reaction, or irritation of the skin. It is caused by the immune system releasing substances that make blood vessels in the skin widen. This makes the irritated area become red, swollen, itchy and painful, as is seen in dermatitis or eczema.