Hyprogel is used in short courses to treat severe inflammatory skin disorders, such as those below, when milder corticosteroids have not been effective.

Psoriasis.
Skin disorder called lichen planus, in which there are patches on the skin that appear as flat-topped, shiny, almost violet itchy areas.
Skin disorder called discoid lupus erythematosus, which is caused by the immune system attacking the skin.